Human papillomavirus (HPV) and somatic EGFR mutations are essential, mutually exclusive oncogenic mechanisms for inverted sinonasal papillomas and associated sinonasal squamous cell carcinomas
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• A papilloma which usually arises from the lateral wall of the nose.• It is benign, but can expand within the closed space and cause pressure necrosis of bone.• SCC may arise from an inverting papilloma.
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