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3-isopropylmalate dehydrogenase


'3-isopropylmalate dehydrogenase' can also refer to...

3‐isopropylmalate dehydrogenase

Cold Adaptation of the Thermophilic Enzyme 3-Isopropylmalate Dehydrogenase

Adaptation of a thermophilic enzyme, 3-isopropylmalate dehydrogenase, to low temperatures

Substrate Recognition of Isocitrate Dehydrogenase and 3-Isopropylmalate Dehydrogenase from Thermus thermophilus HB8

High thermal stability of 3-isopropylmalate dehydrogenase from Thermus thermophilus resulting from low ΔΔC p of unfolding

Cold-adaptation mechanism of mutant enzymes of 3-isopropylmalate dehydrogenase from Thermus thermophilus

A mutation at the interface between domains causes rearrangement of domains in 3-isopropylmalate dehydrogenase.

Relationship between thermal stability and 3-D structure in a homology model of 3-isopropylmalate dehydrogenase from Escherichia coli

Crystal Structure of 3-Isopropylmalate Dehydrogenase from the Moderate Facultative Thermophile, Bacillus coagulans: Two Strategies for Thermostabilization of Protein Structures

Crystal structures of 3-isopropylmalate dehydrogenases with mutations at the C-terminus: crystallographic analyses of structure–stability relationships

The initial step of the thermal unfolding of 3-isopropylmalate dehydrogenase detected by the temperature-jump Laue method

Increased thermal stability against irreversible inactivation of 3‐isopropylmalate dehydrogenase induced by decreased van der Waals volume at the subunit interface

Analysis of the effect of accumulation of amino acid replacements on activity of 3-isopropylmalate dehydrogenase from Thermus thermophilus

Sequence and homology model of 3-isopropylmalate dehydrogenase from the psychrotrophic bacterium Vibrio sp. I5 suggest reasons for thermal instability.

Random mutagenesis improves the low-temperature activity of the tetrameric 3-isopropylmalate dehydrogenase from the hyperthermophile Sulfolobus tokodaii

The Effects of Mutations at Position 253 on the Thermostability of the Bacillus subtilis 3-Isopropylmalate Dehydrogenase Subunit Interface

Ancestral Residues Stabilizing 3-Isopropylmalate Dehydrogenase of an Extreme Thermophile: Experimental Evidence Supporting the Thermophilic Common Ancestor Hypothesis

 

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EC 1.1.1.85; systematic name: 3‐carboxy‐2‐hydroxy‐4‐methylpentanoate:NAD+ oxidoreductase; an enzyme that catalyses the oxidation of 3‐isopropylmalate by NAD+ (followed by loss of CO2) to 4‐methyl‐2‐oxopentanoate, in the pathway of l‐leucine biosynthesis in plants. See leucine and valine biosynthesis.

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Subjects: Chemistry.


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