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2-isopropylmalate synthase


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EC 4.1.3.12; systematic name: 3‐carboxy‐3‐hydroxy‐4‐methylpentanoate 3‐methyl‐2‐oxobutanoate‐lyase (CoA‐acetylating); an enzyme that condenses acetyl‐CoA with 3‐methyl‐2‐oxobutanoate to form 2‐isopropylmalate, in the pathway of l‐leucine biosynthesis in plants. See leucine and valine biosynthesis.

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Subjects: Chemistry.


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