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jingzhaotoxin-III


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A peptide toxin (JZTX-III, 34 aa), isolated from the venom of the Chinese spider Chilobrachys jingzhao, that inhibits voltage-gated sodium channels of rat cardiac myocytes by modifying voltage-dependent gating and also binds to Kv2.1 channel, acting in a similar fashion to hanatoxin1 and SGTx1.

Subjects: Medicine and Health.


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