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kistrin


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A disintegrin (68 aa) isolated from the venom of the Malayan pit viper Agkistrodon rhodostoma. It has an RGD motif that selectively binds to αvβ3 integrin and competes for the platelet IIb/IIIa glycoprotein, thereby inhibiting platelet aggregation.

Subjects: Chemistry — Medicine and Health.


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