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In cytogenetics, a heavily staining enlarged chromomere that may serve as a landmark, allowing certain chromosomes to be identified readily in the nucleus. In maize, knobbed chromatids preferentially enter the outer cells of a linear set of four megaspores during megasporogenesis and are therefore more likely to be included in the egg nucleus (see meiotic drive); genetic markers close to a knob tend to appear more frequently in gametes than those far from a knob.

Subjects: Genetics and Genomics.

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