Krüppel-like factor

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'Krüppel-like factor' can also refer to...

Krüppel‐like factor

Krüppel-like factors

erythroid Krüppel-like factor

erythroid Krüppel-like factor

Opposing effects of Krüppel-like factor 4 (gut-enriched Krüppel-like factor) and Krüppel-like factor 5 (intestinal-enriched Krüppel-like factor) on the promoter of the Krüppel-like factor 4 gene

Krüppel-like factor 15 regulates BMPER in endothelial cells

Differential role for IL‐7 in inducing lung Kruppel‐like factor (Kruppel‐like factor 2) expression by naive versus activated T cells

Characterization of the structure and regulation of the murine gene encoding gut-enriched Krüppel-like factor (Krüppel-like factor 4)

Sports or statins for atheroprotection? New insight from Kruppel-like factor 2

Roles of Krüppel-like factor 4 in normal homeostasis, cancer and stem cells

Krüppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells

Krüppel-like factor 4 expression in normal and pathological human testes

Identification of the DNA sequence that interacts with the gut-enriched Krüppel-like factor

A novel regulator of human villous trophoblast fusion: the Krüppel-like factor 6

Transactivation and growth suppression by the gut-enriched Krüppel-like factor (Krüppel-like factor 4) are dependent on acidic amino acid residues and protein–protein interaction

Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2

The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma

Krüppel-like Factor 4 is Required for the Expression of Vascular Smooth Muscle Cell Differentiation Marker Genes Induced by All-Trans Retinoic Acid

Histone deacetylase 5 interacts with Krüppel-like factor 2 and inhibits its transcriptional activity in endothelium


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A subfamily of transcription factors that have three Krüppel-like zinc fingers. Tissue-specific forms include erythroid Krüppel-like factor (KLF1); gut-enriched Krüppel-like factor (GKLF; KLF4). KLF2 regulates T-cell quiescence and survival and is essential for T-cell trafficking; KLF5 is important in regulating myosin production in vascular smooth muscle; KLF6 is mutated in a subset of human prostate and gastric cancers; KLF7 is ubiquitious; KLF8 mediates cell cycle progression downstream of focal adhesion kinase (FAK) by upregulating cyclin D1. Mutations in KLF11 are associated with early-onset type 2 diabetes. KLF13 regulates RANTES genes; KLF15 is an inhibitor of cardiac hypertrophy; KLF16 regulates the expression of dopamine receptor genes.

Subjects: Medicine and Health.

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