La protein

'La protein' can also refer to...

La protein

Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation

A bona fide La protein is required for embryogenesis in Arabidopsis thaliana

La protein has a positive effect on the translation of TOP mRNAs in vivo

TEXtopo: shaded membrane protein topology plots in LaTEX2ε

Conservation of RNA chaperone activity of the human La-related proteins 4, 6 and 7

Mono-(2-ethylhexyl) Phthalate Rapidly Increases Celsr2 Protein Phosphorylation in HeLa Cells via Protein Kinase C and Casein Kinase 1

Fluorescence Cross-Correlation Analyses of the Molecular Interaction between an Aux/IAA Protein, MSG2/IAA19, and Protein–Protein Interaction Domains of Auxin Response Factors of Arabidopsis Expressed in HeLa Cells

N.B. La Thangue, L.R. Bandara (eds). Targets for Cancer Chemotherapy: Transcription Factors and Other Nuclear Proteins

Heat shock protein 90 mediates the apoptosis and autophage in nicotinic-mycoepoxydiene-treated HeLa cells

Binding of host extracellular matrix proteins to Mycoplasma fermentans and its effect on adherence to, and invasion of HeLa cells

Effects of Adenosine Dialdehyde Treatment on In Vitro and In Vivo Stable Protein Methylation in HeLa Cells

Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein

Partial reconstitution of human RNase P in HeLa cells between its RNA subunit with an affinity tag and the intact protein components

Evidence for a HeLa Nuclear Protein That Binds Specifically to the Single-Stranded d(CCCTAA)n Telomeric Motif

Heat shock of HeLa cells inactivates a nuclear protein phosphatase specific for dephosphorylation of the C-terminal domain of RNA polymerase II

La Protein Required for Internal Ribosome Entry Site—Directed Translation Is a Potential Therapeutic Target for Hepatitis C Virus Replication

The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5′TOP sequence

Cellular Distribution of a GPI-Anchored Complement Regulatory Protein CD59: Homodimerization on the Surface of HeLa and CD59-Transfected CHO Cells


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A protein (La autoantigen, La ribonucleoprotein domain family 3, LARP3, 408 aa) that is involved in diverse aspects of RNA metabolism, including binding and protecting RNA that has been newly synthesized by polymerase III, stabilizing nascent pre-tRNAs from nuclease degradation, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. It is the nuclear autoantigen in patients suffering from Sjögren's syndrome, systemic lupus erythematosus, and neonatal lupus. La-related protein (LARP1) has an RNA-binding domain similar to that of La protein and a second conserved domain, the LARP1 domain, which also has RNA-binding ability. Other LARPs have been found; e.g. LARP7 is a negative transcriptional regulator of polymerase II genes.

Subjects: Medicine and Health.

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