Overview

LE cells


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Cells found in smears of blood mixed with serum samples from patients with systemic lupus erythematosus (SLE). They are phagocytes, usually neutrophils, with one or more large inclusion bodies (LE bodies), composed of DNA and antinuclear antibody, which displace the nucleus to one side. The LE cell reaction is an in vitro test for SLE in which leucocytes are incubated with test serum.

Subjects: Medicine and Health.


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