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A soluble enzyme (lecithin:cholesterol acyltransferase, EC, 416 aa) that converts cholesterol and phosphatidylcholines to cholesteryl esters and lysophosphatidylcholines on the surface of high density lipoproteins. Complete loss of LCAT causes autosomal recessive LCAT deficiency; partial loss causes the autosomal recessive disorders fish eye disease and Norum's disease.

Subjects: Chemistry — Medicine and Health.

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