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Lesch-Nyhan syndrome


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A hereditary disorder of purine metabolism, affecting young boys, transmitted by a sex-linked recessive gene, characterized by mental retardation, self-mutilation of lips and fingers by biting, and abnormal physical development, often leading to death. [Named after the US paediatricians Michael Lesch (1939–2008) and William L. Nyhan, Jr (born 1926), who first studied it]

Subjects: Science and Mathematics.


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