leukemia inhibitory factor

'leukemia inhibitory factor' can also refer to...

leukemia inhibitory factor

Structure of the Gene Encoding the Human Differentiation-Stimulating Factor/Leukemia Inhibitory Factor Receptor

miRNA-181 regulates embryo implantation in mice through targeting leukemia inhibitory factor

Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations

Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioids

Leukemia inhibitory factor is augmented in the heart in experimental heart failure

Functions of the N-Glycans of Rat Leukemia Inhibitory Factor Expressed in Chinese Hamster Ovary Cells

Intracellular Localization of Migration Inhibitory Factor-Related Protein (MRP) and Detection of Cell Surface MRP Binding Sites on Human Leukemia Cell Lines

Expression of leukemia inhibitory factor and its receptor is not altered in the decidua and chorionic villi of human anembryonic pregnancy

Leukemia inhibitory factor promotes human first trimester extravillous trophoblast adhesion to extracellular matrix and secretion of tissue inhibitor of metalloproteinases-1 and -2

Induction of prostaglandin E2 production by leukemia inhibitory factor promotes migration of first trimester extravillous trophoblast cell line, HTR-8/SVneo

Epitope-function relationships of human leukemia inhibitory factor receptors using a novel set of anti-gp190 mAB.

Human chorionic gonadotropin and growth factors at the embryonic–endometrial interface control leukemia inhibitory factor (LIF) and interleukin 6 (IL-6) secretion by human endometrial epithelium

Low microRNA-199a expression in human amniotic epithelial cell feeder layers maintains human-induced pluripotent stem cell pluripotency via increased leukemia inhibitory factor expression


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A cytokine (202 aa) that regulates growth and differentiation of primordial germ cells and embryonic stem cells but also has effects on peripheral neurons, osteoblasts, adipocytes, and various cells of the myeloid lineage. Can induce weight loss, behavioural disorders, and bone abnormalities in adults. Many of the effects of LIF in vitro can be mimicked by interleukin-6, oncostatin M, and ciliary neurotrophic factor, all of which interact indirectly with gp130, a shared tranducer subunit. Not to be confused with leucocyte inhibitory factor (leucocyte migration inhibitory factor), an operational definition of an activity rather than a distinct factor.

Subjects: Medicine and Health — Chemistry.

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