ligand-gated ion channel

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An ion channel that responds to binding of a specific ligand, typically a neurotransmitter at a chemical synapse, by changing its properties and allowing an increase in the flow of ions across the membrane. The change may be from almost zero permeability when closed, to allowing passage of 107 ions per second when open. Examples are the acetylcholine and GABA receptors.

Subjects: Science and Mathematics — Medicine and Health.

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