Overview

ligase amplification reaction


Related Overviews

 

'ligase amplification reaction' can also refer to...

 

More Like This

Show all results sharing this subject:

  • Medicine and Health

GO

Show Summary Details

Quick Reference

A method analogous to the polymerase chain reaction (PCR) used to detect small quantities of a target DNA. The method relies upon the requirement, by DNA ligase, for sequence similarity to allow ligation of synthetic oligonucleotides (probe) bound to target DNA. Various ligase-based techniques have been developed for the high-throughput detection of DNA, homogeneous assays, single-molecular detection, and scanning of unknown mutations.

Subjects: Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.