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Large loop excision of the transformation zone: a procedure for treating premalignant conditions of the cervix, including carcinoma in situ (CIN3; see cervical intraepithelial neoplasia), that is performed under colposcopic control (see colposcopy) after application of local anaesthetic to the cervix. The transformation zone is removed using a thin loop of wire heated by electric current (see diathermy).

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