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lock-and-key theory


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A theory to explain the mechanism of enzymatic reactions, in which it is proposed that the enzyme and substrate(s) bind temporarily to form an enzyme–substrate complex. The binding site on the enzyme is known as the ‘active site’ and is structurally complementary to the substrate(s). Thus the enzyme and substrate(s) are said to fit together as do a lock and a key.

Subjects: Biological Sciences — Chemistry.


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