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lumefantrine


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lumefantrine

Coartem (Artemether-Lumefantrine) in Africa: The Beginning of the End?

Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria

Adherence to artemether/lumefantrine treatment in children under real-life situations in rural Tanzania

Case report: combination artemether-lumefantrine and haemolytic anaemia following a malarial attack

Update on the in vivo tolerance and in vitro reduced susceptibility to the antimalarial lumefantrine

Dynamics of Plasmodium falciparum Selection After Artemether-Lumefantrine Treatment in Africa

Malaria Transmission After Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine: A Randomized Trial

Adherence to Treatment With Artemether-Lumefantrine for Uncomplicated Malaria in Rural Malawi

Efficacy and safety of artemether–lumefantrine (Coartem®) tablets (six-dose regimen) in African infants and children with acute, uncomplicated falciparum malaria

An integrated assessment of the clinical safety of artemether-lumefantrine: a new oral fixed-dose combination antimalarial drug

In Vivo Selection of Plasmodium falciparum Parasites Carrying the Chloroquine-Susceptible pfcrt K76 Allele after Treatment with Artemether-Lumefantrine in Africa

In Vivo Selection of Plasmodium falciparum pfmdr1 86N Coding Alleles by Artemether-Lumefantrine (Coartem)

Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults

Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin

Prolonged Selection of pfmdr1 Polymorphisms After Treatment of Falciparum Malaria With Artemether-Lumefantrine in Uganda

Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults

Effectiveness of Artemether/Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax and P. falciparum Malaria in Young Children in Papua New Guinea

Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-Lumefantrine Versus Dihydroartemisinin-Piperaquine for the Treatment of Malaria

 

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A synthetic antimalarial drug (TN Benflumetol) frequently used in combination with artemether, a drug related to artemisinin. The combined therapy is advantageous because artemether is rapid-acting but short-lived and lumefantrine is slow-acting but with a long half-life in patients. The combination is distributed as Riamet™.

Subjects: Medicine and Health.


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