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lymphocyte activation


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The altered shape and behaviour of lymphocytes which have been exposed to a mitogen or an antigen to which they have been primed. The activation leads to the production of lymphoblasts which divide and form a population of effector cells. Sometimes referred to as lymphocyte transformation, but the transformation is unlike that caused by oncogenic viruses (see transformation) and activation is a less confusing term.

Subjects: Medicine and Health.


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