macrophage activation syndrome

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A severe, potentially lethal condition in which there is excessive activation of well-differentiated macrophages. It is associated with Still's disease and considered by some to be autoimmune disease-associated reactive haemophagocytic lymphohistiocytosis (ReHLH), a subset of haemophagocytic lymphohistiocytosis. See MAF (macrophage activating factor).

Subjects: Medicine and Health.

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