major groove

'major groove' can also refer to...

major groove

Minor Groove DNA Alkylation Directed by Major Groove Triplex Forming Oligodeoxyribonucleotides

A click chemistry approach towards nucleic acid major groove functionalization

Structures of an all-α protein running along the DNA major groove

Synthesis of structurally diverse major groove DNA interstrand crosslinks using three different aldehyde precursors

Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases

Zn2+ selectively stabilizes FdU-substituted DNA through a unique major groove binding motif

Functional significance of the TATA element major groove in transcription initiation by RNA polymerase II

RNA major groove modifications improve siRNA stability and biological activity

Nucleic acid duplexes with zippers of additional nucleobases and aromatics in minor or major groove

Assessment of Major and Minor Groove DNA Interactions by the Zinc Fingers of Xenopus Transcription Factor IIIA

Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics

Hexahydrated magnesium ions bind in the deep major groove and at the outer mouth of A-form nucleic acid duplexes

Site-specific targeting of aflatoxin adduction directed by triple helix formation in the major groove of oligodeoxyribonucleotides

An NMR and molecular modelling analysis of d(CTACTGCTTTAG)·d(CTAAAGCAGTAG) reveals that the particular behaviour of TpA steps is related to edge-to-edge contacts of their base-pairs in the major groove


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Quick Reference

The larger and deeper of the two spiral grooves on the surface of a double‐helical b‐DNA molecule. Compare minor groove.

Subjects: Chemistry.

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