Dangerously high blood pressure (diastolic pressure >130 mmHg) associated with necrosis of small arteries and arterioles. Retinal haemorrhage and papilloedema are present. Untreated, malignant hypertension causes severe organ damage, targeting the central nervous and cardiovascular systems and the kidneys (malignant nephrosclerosis). Causes include complications of essential and secondary hypertension and pregnancy and the use of certain drugs (e.g. MAO inhibitors).
Subjects: Medicine and Health.