manifesting heterozygote

'manifesting heterozygote' can also refer to...


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A female heterozygous for a sex-linked recessive mutant gene who expresses the same phenotype as a male hemizygous for the mutation. This rare phenomenon results from the situation where, by chance, most somatic cells critical to the expression of the mutant phenotype contain an inactivated X chromosome carrying the normal allele of the gene. See Lyonization.

Subjects: Genetics and Genomics.

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