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A very rare congenital deficiency of α-mannosidase, an enzyme which breaks down the sugar mannose. It is characterized by learning disabilities and a susceptibility to infection, together with changes in facial features such as a prominent forehead, a flattened nasal bridge, a small nose, and a broad mouth.

http://www.mpssociety.co.uk The Society for Mucopolysaccharide diseases website, which provides information on the causes and treatment of mannosidosis.

Subjects: Dentistry.

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