Overview

MAPK phosphatase


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A family of phosphatases (MKPs) that regulate MAP kinases (MAPKs) by removing phosphate on tyrosine and threonine in the -pTXpY- activation loop (dual specificity phosphatases). Different members of the family have specificities for various MAPKs, are located in different tissues and subcellular sites, and are induced by different extracellular stimuli.

Subjects: Medicine and Health.


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