A mathematical formula developed by J. B. S. Haldane that relates map distances to recombination frequencies. The function is represented graphically below. It demonstrates that no matter how far apart two genes are on a chromosome, one never observes a recombination value greater than 50%. It also shows that the relation between recombination frequencies and map distances is linear for genes that recombine with frequencies less than 10%.
Subjects: Genetics and Genomics.