Marburg disease

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Syn: African hemorrhagic fever. A dangerous hemorrhagic fever caused by a filovirus possibly carried by African monkeys that was first identified as a specific disease in Marburg, Germany, in 1967. In Central Africa, it has a case fatality rate ranging from 25% to 80%. Like Ebola virus disease, it can occur in epidemic form with very high case fatality rate, as in Angola in 2005. There is no effective antiviral therapy and no approved vaccine, although an experimental vaccine has been shown to be effective in infected monkeys. Information including current surveillance data is at http://www.who.int/csr/disease/marburg/en/.

Subjects: Public Health and Epidemiology.

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