M channels

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M channels

Ischaemic and morphine-induced post-conditioning: impact of mKCa channels

Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium

Regulation of the epithelial Na+ channel by the mTORC2/SGK1 pathway

Eukaryotic translational termination efficiency is influenced by the 3′ nucleotides within the ribosomal mRNA channel

Subunit-specific contribution to agonist binding and channel gating revealed by inherited mutation in muscle acetylcholine receptor M3–M4 linker

ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue

William M. LeoGrande and Peter Kornbluh. Back Channel to Cuba: The Hidden History of Negotiations between Washington and Havana.

The relative order of mKATP channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart

Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma

Ca2+ Influx into Lily Pollen Grains Through a Hyperpolarization-activated Ca2+-permeable Channel Which Can be Regulated by Extracellular CaM

Insights from studying the mutation-induced allostery in the M2 proton channel by molecular dynamics

A method for the simultaneous analysis of mRNA levels of multiple cardiac ion channels with a multi-probe RNase protection assay

Identification of a Mg2+-sensitive ORF in the 5′-leader of TRPM7 magnesium channel mRNA

HIV-1 frameshift efficiency is primarily determined by the stability of base pairs positioned at the mRNA entrance channel of the ribosome

L-type voltage-dependent calcium channel α-1C subunit mRNA is present in ejaculated human spermatozoa*

Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability

Intrinsic lidocaine affinity for Na channels expressed in Xenopus oocytes depends on α (hH1 vs. rSkM1) and β1 subunits


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A set of slowly activating and deactivating voltage-sensitive potassium channels, responsible for the M current in neurons, encoded by KV7.2–KV7.5/KCNQ2–KCNQ5 genes. They are inactivated by acetylcholine and regulate the sensitivity of neurons to synaptic input. Mutations in KCNQ2 and KCNQ3, channels that interact functionally with each other, are associated with benign neonatal epilepsy. The KCNQ4 gene product is expressed in cochlear hair cells and mutations are associated with deafness. The KCNQ5 gene product seems to be widely expressed and presumably contributes to variation in the properties of M channels in different neurons. Linopiridine is a selective M-current blocker.

Subjects: Medicine and Health.

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