melanin pigmentation

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A change in the amount of melanin produced. It may be developmental (see melanocytic naevus; Peutz-Jeghers syndrome; café au lait spots) or acquired as the result of systemic disease (see Addison's disease), malignancy (see melanoma), or a simple local disorder (see melanotic macule). Pigmentation of the soft palate is associated with smoking and bronchiogenic carcinoma. Certain drugs may also cause oral pigmentation.

Subjects: Dentistry.

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