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Zinc metalloendopeptidases of the astacin family (endopeptidase 2, EC that degrade a wide variety of signalling peptides such as bradykinin and TGFα, and extracellular matrix components. Meprin A has both α and β subunits and is secreted; meprin B contains only β subunits and is plasma membrane associated.

Subjects: Medicine and Health.

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