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mepyramine


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An antihistamine drug used to treat insect bites and nettle stings by topical application. Appears to be an inverse agonist of the histamine H1 receptor (mepyramine binds with high affinity to a Gq/11-protein-coupled form of the receptor and reduces G-protein availability for other receptors in the signalling pathway).

Subjects: Clinical Pharmacology and Therapeutics.


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