Overview

mesothelin


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A GPI-linked cell surface glycoprotein (megakaryocyte potentiating factor, 630 aa), first identified as the target for monoclonal antibody K1, strongly expressed in normal mesothelial cells, mesotheliomas, nonmucinous ovarian carcinomas, and some other malignancies. Mesothelin function is not essential for growth or reproduction in mice.

Subjects: Medicine and Health.


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