methionine aminopeptidase

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A mitochondrial metallopeptidase (MAP1, EC, 478 aa) that removes the N-terminal methionine from proteins, facilitating further modification. Methionine aminopeptidase 2 (eukaryotic initiation factor-2 (eIF-2)-associated protein; p67) is the target for the antiangiogenic drug fumagillin.

Subjects: Medicine and Health.

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