methylCpG-binding protein 2

'methylCpG-binding protein 2' can also refer to...

methyl-CpG-binding protein 2

methylCpG‐binding protein 2

Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)

Methyl CpG binding protein 2 (MeCP2) enhances photodimer formation at methyl-CpG sites but suppresses dimer deamination

Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2

5-Halogenated pyrimidine lesions within a CpG sequence context mimic 5-methylcytosine by enhancing the binding of the methyl-CpG-binding domain of methyl-CpG-binding protein 2 (MeCP2)

Methyl deficiency causes reduction of the methyl-CpG-binding protein, MeCP2, in rat liver

Transcriptional regulation in pluripotent stem cells by methyl CpG-binding protein 2 (MeCP2)

Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry

A partial loss of function allele of Methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

DOP004. Epigenetic control of colonic epithelial antigen processing, barrier function, and the microbiome via methyl-CpG binding domain protein 2

Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription

An intrinsically disordered region of methyl-CpG binding domain protein 2 (MBD2) recruits the histone deacetylase core of the NuRD complex

Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells

A Complex Pattern of Evolutionary Conservation and Alternative Polyadenylation Within the Long 3′-Untranslated Region of the Methyl-CpG-Binding Protein 2 Gene (MeCP2) Suggests a Regulatory Role in Gene Expression


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A protein (MeCP2, 486 aa) that binds to methylated CpG-rich regions of DNA and that contributes to silencing (see DNA methylation and genomic imprinting). MeCP2 regulates gene expression in neurons and is important in neurogenesis. The X-linked gene is mutated in Rett's syndrome and some cases of Angelman's syndrome.

Subjects: Chemistry — Medicine and Health.

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