Overview

MIM


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A G-actin binding protein (missing in metastasis, metastasis suppressor 1, 356 aa) with greater affinity for ATP-actin than for ADP-actin. Contains a WH2 domain and interacts directly with the SH3 domain of cortactin. MIM appears to regulate cell motility by modulation of Arp2/3 activators.

Subjects: Medicine and Health.


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