A process in which a diploid cell undergoing mitosis gives rise to daughter cells with allele combinations different from that in the parental cell. As in meiotic recombination, mitotic recombination generally involves genetic exchange between chromatids of homologous chromosomes, but occurs less frequently than meiotic recombination. Mitotic recombination can give rise to tissues that are genetic mosaics, including tissues with twin spots (q.v.), and can be experimentally induced. See Chronology, 1936, Stern; gene targeting, homologous recombination, somatic crossing over.
Subjects: Genetics and Genomics — Chemistry.