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Moloney murine sarcoma virus


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A replication-defective retrovirus that will induce fibrosarcomas in vivo, and transform cells in culture. It arose by recombination between the Moloney murine leukaemia virus and a sequence (v-mos oncogene) derived from mouse cells and required for induction and maintenance of viral transformation; the human homologue was subsequently identified. See mos.

Subjects: Medicine and Health.


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