M5 technique

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A technique used to detect induced sex-linked lethal and viable mutations in Drosophila melanogaster. The technique gets its name from the X chromosome used to balance the chromosomes bearing the induced mutations. The M5 or Muller 5 chromosome is the fifth of a series synthesized by H. J. Muller. It contains a complex inversion and the marker genes Bar, apricot, and scute. For this reason, the M5 chromosome is sometimes abbreviated Basc. See balanced stock.

Subjects: Genetics and Genomics.

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