Overview

multiple myeloma oncogene-1


Related Overviews

 

'multiple myeloma oncogene-1' can also refer to...

 

More Like This

Show all results sharing this subject:

  • Medicine and Health

GO

Show Summary Details

Quick Reference

An oncogene encoding a protein (interferon regulatory factor 4, IRF4, 405 aa) that interacts with myd88 and is involved in a regulatory pathway for B-cell proliferation and differentiation. This regulatory system is aberrant in most myelomas, although the IRF4 is not altered itself. In some cases IRF4 is overproduced as a result of a chromosomal translocation that puts it next to the immunoglobulin heavy chain locus. See IRFs.

Subjects: Medicine and Health.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.