Overview

MutL


'MutL' can also refer to...

MutL

Thermus thermophilus MutS2, a MutS Paralogue, Possesses an Endonuclease Activity Promoted by MutL

Site‐specific protein modification to identify the MutL interface of MutH

ATP hydrolysis-dependent formation of a dynamic ternary nucleoprotein complex with MutS and MutL

Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair

The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA

Analysis of DNA structure and sequence requirements for Pseudomonas aeruginosa MutL endonuclease activity

Dominant Negative Mutator Mutations in the mutL Gene of Escherichia Coli

Physical and functional interactions between Escherichia coli MutL and the Vsr repair endonuclease

The sliding clamp tethers the endonuclease domain of MutL to DNA

Identifying an interaction site between MutH and the C-terminal domain of MutL by crosslinking, affinity purification, chemical coding and mass spectrometry

mutL as a genetic switch of bacterial mutability: turned on or off through repeat copy number changes

Mutation rate is reduced by increased dosage of mutL gene in Escherichia coli K-12

Structural Insights of the Nucleotide-Dependent Conformational Changes of Thermotoga maritima MutL Using Small-Angle X-ray Scattering Analysis

Human MutL homolog (MLH1) function in DNA mismatch repair: a prospective screen for missense mutations in the ATPase domain

The DNA mismatch-repair MLH3 protein interacts with MSH4 in meiotic cells, supporting a role for this MutL homolog in mammalian meiotic recombination

The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2

 

More Like This

Show all results sharing this subject:

  • Chemistry

GO

Show Summary Details

Quick Reference

A protein of E. coli that is involved, with MutS and MutH, in DNA mismatch repair. MutL homologues (abbr.: MLH) are present in all eukaryotic cells. Mutations in the human homologue (hMLH) are common in hereditary nonpolyposis colon cancer.

[...]

Subjects: Chemistry.


Reference entries

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.