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n. a chronic but progressive disease characterized by fibrosis of the bone marrow, which leads to anaemia and the presence of immature red and white blood cells in the circulation. Other features include enlargement of the spleen and the presence of blood-forming (myeloid) tissue in abnormal sites, such as the spleen and liver (extramedullary haemopoiesis). Its cause is unknown.

Subjects: Medicine and Health.

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