Overview

myeloma cell


'myeloma cell' can also refer to...

myeloma cell

NS‐1 myeloma cells

NS-1 myeloma cells

Idiotype vaccination in patients with myeloma reduced circulating myeloma cells (CMC)

Bone marrow and peripheral blood stem cell transplantation in multiple myeloma

Characterization of MYC Translocations in Multiple Myeloma Cell Lines

Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells

Allogeneic T lymphocytes as a source of peptide-dependent T cells specific for myeloma cells

Myeloma cells resistance to NK cell lysis mainly involves an HLA class I-dependent mechanism

Biological modifiers as cytoreductive therapy before stem cell transplant in previously untreated patientswith multiple myeloma

High-dose therapy with peripheral blood progenitor cell transplantation in multiple myeloma

A quantitative PCR assay for the detection of low amounts of malignant cells in multiple myeloma*

Efficacy of Up-Front Treatment with a Double Stem Cell Transplantation in Multiple Myeloma

Researchers Debate Best Use of Stem Cell Transplants in Patients With Multiple Myeloma

StatBite: Multiple Myeloma and African Americans: Higher Incidence But Fewer Autologous Stem Cell Transplants

Potentiation of (−)-epigallocatechin-3-gallate-induced apoptosis by bortezomib in multiple myeloma cells

Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells

Promoter hypermethylation of tetraspanin members contributes to their silencing in myeloma cell lines

Myeloma light chains induce epithelial-mesenchymal transition in human renal proximal tubule epithelial cells

 

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A neoplastic plasma cell. In multiple myeloma the proliferating plasma cells dominate the marrow, leading to immune deficiency and often destruction of surrounding bone. Various molecular events can cause the disorder, including dysregulation of oncogenes by translocations to the IgH locus, mutations in genes encoding cyclin D1 and fibroblast growth factor receptor-3. (See also multiple myeloma oncogene-1.) Myeloma cells are monoclonal and therefore secrete a single type of immunoglobulin, a characteristic exploited in the production of monoclonal antibodies by hybridoma cells; see Bence Jones protein.

Subjects: Medicine and Health.


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