The genes encoding the isoforms of the heavy and light myosin chains. In Drosophila, two myosin heavy chain genes have been identified: one encoding a muscle myosin (Mhc) and one encoding a cytoplasmic myosin (Mhc-c). The transcription unit of Mhc is 22 kilobases long and contains 19 different exons. Multiple transcripts are generated by alternative splicing (q.v.). Genes for the two light chains are also known. In mammals, the muscle myosin heavy chain isoforms are encoded by a family containing at least 10 genes.
Subjects: Genetics and Genomics.