Overview

myosin light chains


'myosin light chains' can also refer to...

myosin light chains

myosin light chain kinase

myosin‐light‐chain kinase

myosin‐light‐chain‐phosphatase

myosin-light-chain kinase

myosin-light-chain-phosphatase

Myosin light chain phosphorylation, novel targets to repair a broken heart?

Myosin light chain kinase in microvascular endothelial barrier function

Human essential myosin light chain isoforms revealed distinct myosin binding, sarcomeric sorting, and inotropic activity

Mutations of ventricular essential myosin light chain disturb myosin binding and sarcomeric sorting

Too light to be essential? Insights from FHC-related mutations in essential myosin light chains

Myosin light chain isoforms modify force-generating ability of cardiac myosin by changing the kinetics of actin–myosin interaction

Calcium-mediated regulation of recombinant hybrids of full-length Physarum myosin heavy chain with Physarum/scallop myosin light chains

Modulation of contractility in human cardiac hypertrophy by myosin essential light chain isoforms

Extracellular ATP induces assembly and activation of the myosin light chain phosphatase complex in endothelial cells

Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms

Myosin light chain phosphorylation facilitates monocyte transendothelial migration by dissociating endothelial adherens junctions

Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers

Conformation and Activity of Smooth Muscle Myosin Probed by Various Essential Light Chains

 

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Two pairs of smaller subunits (17–22 kDa) of hexameric myosin II, each pair being different. The two regulatory light chains (LC-2, DNTB light chains, MYL2 gene products) may directly confer calcium sensitivity on the ATPase activity, or indirectly when they are phosphorylated by calcium-regulated myosin light chain kinase. Essential light chains (LC-1, LC-3; alkali light chains, MYL3 gene products) may have a partly structural role. Multiple tissue-specific variants exist. Mutation in the gene for the essential light chains causes some types of hypertrophic cardiomyopathy.

Subjects: Medicine and Health.


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