Enzymes that catalyse the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). The NADPH oxidase activator, NOXA1 (p51-NOX, 476 aa), can stimulate both NOX1 and NOX2 (p91phox, 570 aa). The NADPH oxidase organizer (NOXO1, p41-NOX, 371 aa) targets NOX activators to NOX and to different subcellular compartments. See phox.
Subjects: Medicine and Health.