NADPH oxidases

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(NOX1, NOX2)

Enzymes that catalyse the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). The NADPH oxidase activator, NOXA1 (p51-NOX, 476 aa), can stimulate both NOX1 and NOX2 (p91phox, 570 aa). The NADPH oxidase organizer (NOXO1, p41-NOX, 371 aa) targets NOX activators to NOX and to different subcellular compartments. See phox.

Subjects: Medicine and Health.

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