(Devic’s disease) a condition that resembles multiple sclerosis. The diagnosis is confirmed by the finding of the antiaquaparin-4 antibody (NMO IgG antibody). Typically there is a transverse myelitis, producing paralysis and numbness of the legs and trunk below the inflamed spinal cord, and retrobulbar (optic) neuritis affecting both optic nerves. The attacks of myelitis and optic neuritis may coincide or they may be separated by days or weeks. Recovery from the initial attack is often incomplete, but relapses appear to be less common than in conventional multiple sclerosis.
Subjects: Medicine and Health.