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A modified methionine molecule that has a formyl group attached to its terminal amino group. Such an amino acid is “blocked” in the sense that the absence of a free amino group prevents the amino acid from being inserted into a growing polypeptide chain. N-formylmethionine is the starting amino acid in the synthesis of all bacterial polypeptides. See Chronology, 1966, Adams and Cappecchi; initiator tRNA, start codon.

Subjects: Chemistry — Genetics and Genomics.

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