nicotinic acetylcholine receptor

'nicotinic acetylcholine receptor' can also refer to...

nicotinic acetylcholine receptor

Nicotinic Acetylcholine Receptor Mutations

nicotinic acetylcholine receptor

Evolution of nicotinic acetylcholine receptor subunits.

Assembly and targeting of neuronal nicotinic acetylcholine receptors

Block of Neuronal Nicotinic Acetylcholine Receptors by Organophosphate Insecticides

Association Between Nicotinic Acetylcholine Receptor Single Nucleotide Polymorphisms and Smoking Cessation

Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers

Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette

Effect of smoking and transdermal nicotine on colonic nicotinic acetylcholine receptors in ulcerative colitis

Pharmacology of neuronal nicotinic acetylcholine receptors: Effect of acute and chronic nicotine

A mixed helix—beta-sheet model of the transmembrane region of the nicotinic acetylcholine receptor

Molecular modelling of the nicotinic acetylcholine receptor transmembrane region in the open state.

Tracking the Molecular Evolution of Calcium Permeability in a Nicotinic Acetylcholine Receptor

Symposium Overview: Mechanism of Action of Nicotine on Neuronal Acetylcholine Receptors, from Molecule to Behavior

Beta2* nicotinic acetylcholine receptors modulate pain sensitivity in acutely abstinent tobacco smokers

Abnormal Social Behavior in Nicotinic Acetylcholine Receptor β4 Subunit–Null Mice

β 2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder

Cotinine binding to nicotinic acetylcholine receptors in bovine chromaffin cell and rat brain membranes


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An integral membrane ion channel in the postsynaptic membrane that opens when it binds acetylcholine. The nicotinic acetylcholine receptor, which is blocked by nicotine, initiates muscle contraction at the neuromuscular junction. The channel is a heteropentamer of related subunits with both the acetylcholine binding site and the ionic channel. The nAChR mediates rapid transduction events (1 ms), unlike G-protein-coupled receptors which operate on millisecond to second time scales. Mutations in various of the subunits cause congenital myasthenic syndrome with either fast or slow channels being affected according to which subunit is affected. See also myasthenia gravis.

Subjects: Medicine and Health.

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