Overview

nicotinic acetylcholine receptor


'nicotinic acetylcholine receptor' can also refer to...

Nicotinic Acetylcholine Receptor Mutations

nicotinic acetylcholine receptor

nicotinic acetylcholine receptor

Evolution of nicotinic acetylcholine receptor subunits.

Assembly and targeting of neuronal nicotinic acetylcholine receptors

Up-regulation of nicotinic acetylcholine receptors in menthol cigarette smokers

Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette

Block of Neuronal Nicotinic Acetylcholine Receptors by Organophosphate Insecticides

Association Between Nicotinic Acetylcholine Receptor Single Nucleotide Polymorphisms and Smoking Cessation

Effect of smoking and transdermal nicotine on colonic nicotinic acetylcholine receptors in ulcerative colitis

Pharmacology of neuronal nicotinic acetylcholine receptors: Effect of acute and chronic nicotine

Layer-Specific Modulation of the Prefrontal Cortex by Nicotinic Acetylcholine Receptors

Functional Expression of Nicotinic Acetylcholine Receptors in Rat Neocortical Layer 5 Pyramidal Cells

Evidence for Nicotinic Acetylcholine Receptors on Nasal Trigeminal Nerve Endings of the Rat

A mixed helix—beta-sheet model of the transmembrane region of the nicotinic acetylcholine receptor

Molecular modelling of the nicotinic acetylcholine receptor transmembrane region in the open state.

PS106. Nicotinic acetylcholine receptor antagonists for treatment-resistant depression: A meta-analysis.

CHRNA4 and ANKK1 Polymorphisms Influence Smoking-Induced Nicotinic Acetylcholine Receptor Upregulation

Tracking the Molecular Evolution of Calcium Permeability in a Nicotinic Acetylcholine Receptor

 

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Quick Reference

(nAChR)

An integral membrane ion channel in the postsynaptic membrane that opens when it binds acetylcholine. The nicotinic acetylcholine receptor, which is blocked by nicotine, initiates muscle contraction at the neuromuscular junction. The channel is a heteropentamer of related subunits with both the acetylcholine binding site and the ionic channel. The nAChR mediates rapid transduction events (1 ms), unlike G-protein-coupled receptors which operate on millisecond to second time scales. Mutations in various of the subunits cause congenital myasthenic syndrome with either fast or slow channels being affected according to which subunit is affected. See also myasthenia gravis.

Subjects: Medicine and Health.


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