Overview

NMDA receptor


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A receptor on synapses that binds the neurotransmitter glutamate and also binds its agonist NMDA (N-methyl-D-aspartate). This receptor is involved in learning, memory, mood, and cognition; its overactivity is associated with chronic pain. NMDA-receptorantagonists (e.g. amantadine, memantine hydrochloride, riluzole) are used in the treatment of (among other conditions) epilepsy, Alzheimer’s disease, and chronic pain syndromes.

Subjects: Medicine and Health.


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