no-observed-adverse-effect level

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In occupational and environmental health, the highest dose at which no adverse effects are observed in an animal population that is challenged with graduated doses of a substance or agent that is known or suspected to be toxic or harmful. In setting safety standards for human exposure, it is usual to set the safety level two or more orders of magnitude above the NOAEL, i.e., 100 or 1,000 times higher.

Subjects: Public Health and Epidemiology.

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