nucleosome remodelling factor complex

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A multisubunit complex (NURF complex) consisting of SMARCA1, BPTF (bromodomain and PHD finger-containing transcription factor, 3046 aa) and the retinoblastoma-binding proteins, RBBP4 and RBBP7, that uses the energy of ATP hydrolysis to catalyse nucleosome sliding, thereby altering chromatin structure and regulating transcription.

Subjects: Medicine and Health.

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